Seronegative Anthropy

Seronegative anthropy gives one with certain clinical characteristics like back pain and unique manifestations that you cannot expect for such disease like uveitis, gastrointestinal symptoms and rashes. Some of these symptoms are strongly associated with the so-called HLA-B27 allele. This disease may even cause you to develop other pathophysiologic conditions. Rheumatoid factor is negative in seronegative anthropy from the word itself seronegative. This even includes ankylosing spondylitis, psoriatic, and reactive arthritis.

Seronegative anthropy is a systemic disorder that affects axial skeleton, large peripheral joints, joints in the hands and arms causing them to be inflamed. And as result, one suffers from nocturnal back pain, kyphosis or convex curving of the back, back stiffness and complications like aortitis, cardiac conduction abnormalities, and uveitis. This disease conditions affect greatly men than women who are aging from 20 to 40 years old. People who have known family history of seronegative anthropy are put at high risk of developing one. Another risk factor is the genetic predisposition since this condition is clinically found out to affect people from Caucasian and Black races.

Individuals who have seronegative anthropy suffer from back pain, peripheral joint pain and other early signs and symptoms such as diminished chest expansion, low-grade fever, fatigue, and weight loss caused by anorexia and anemia. Back pain in seronegative anthropy is expected to occur during the night and varies in intensity that eventually recurs. Patient may also complain morning stiffness that typically is relieved by activity and as this disease continues to worsen, this may lead to paraspinal muscle spasm. Back arching or bent-over posture helps a patient to be relieved from back pain and paraspinal muscle spasm. This practice may help in a way though, however this develop to another complication termed as kyphosis. The patient then eventually develops severe hip arthritis. And in the late stages, accentuated kyphosis and loss of lumbar lordosis happen which then put pulmonary functions in jeopardy and making the patient to barely lie flat on his or her back.  Systemic signs and symptoms are seen in 33% of patients. Recurrent and acute anterior uveitis is common but cases of impaired vision are rare. Manifestation in neurologic part is occasional as a result of radiculitis or sciatica compression, vertebral fracture and other disease conditions that affect the spinal cord. Cardiovascular manifestations are also can be expected like aortic insufficiency, angina, pericarditis, and cardiac conduction abnormalities.

You can determine if you are suffering from seronegative anthropy by series of test. Diagnostic tests include lumbosacral spine imaging and blood tests like ESR, C-reactive protein and CBC.

Treatment for seronegative anthropy includes administration of NSAIDs or Non-Steroidal Anti-Inflammatory Drugs and physical measures like rehabilitation and range of motion exercises to maintain joint flexibility. With proper treatment, disease manifestations will be minimal and even disability will be prevented.

Here is some related info you may be interested in:
Arthritis Natural Remedies
Seronegative Arthritis
Seronegative Arthritis Emedecine

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